CENTER FOR METABOLISM AND MITOCHONDRIAL MEDICINE
   

The 7th Regional

TRANSLATIONAL RESEARCH ON
MITOCHONDRIA, METABOLISM, AGING, AND
DISEASE SYMPOSIUM (TRiMAD)

OCTOBER 5 & 6, 2017

 
 

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Agenda

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Thursday, October 5, 2017


8:00am

Breakfast & Registration - University Club Ballroom B

 

 

8:30am

Welcome / Opening Remarks

Arthur Levine, MD
Sruti Shiva, PhD
Ben Van Houten, PhD

 

 

8:45-9:45am

KEYNOTE LECTURE - Toren Finkel, MD, PhD (UPitt)
“Mitochondria, metabolism and aging”

 

 

10:00am-12:25pm

SYMPOSIUM 1: NEURODEGENERATION
Session Chair: Ed Burton, MD, PhD (UPitt)

10:00-10:25

Sarah Berman, MD, PhD (UPitt) - "Mitochondrial dynamics in Parkinson's disease"

10:25-10:50

Martin Picard, PhD (Columbia U) - "Oncogenic spread of mutant mtDNA intracellularly in mitochondrial disease and aging"

10:50-11:15

Andrew Wojtovich, PhD (U of Rochester) - "Optogenetic control of mitochondrial ROS microdomains"

11:15-11:40

Ed Burton, MD, PhD (UPitt) - "Interactions between α-synuclein and mitochondria in Parkinson’s disease"

11:40-12:05

Patty Opresko, PhD (UPitt) - "A new tool for examining crosstalk between telomere and mitochondrial dysfunction"

12:05-12:25

Kevin Bittman, PhD (Seahorse/Agilent) - "The Agilent Seahorse XF Analyzer advances the study of metabolism"

 

 

12:30-2:00pm

LUNCH / POSTERS / NETWORKING TIME

   

2:00-4:15pm

SYMPOSIUM 2: LIPID METABOLISM
Session Chair: Eric Goetzman, PhD (UPitt)

2:00-2:25

Eric Goetzman, PhD (UPitt) - "Sirt5 and peroxisomal fatty acid oxidation during acute kidney injury"

2:25-2:50

Ed Prochownik, PhD (UPitt) - "Efficient normal and neoplastic proliferation after genetic dissociation of glycolysis and the TCA cycle"

2:50-3:15

Sruti Shiva, PhD (UPitt) - "Platelet bioenergetics"

3:15-3:25

Abstract Talk: Dhanendra Tomar, PhD (Temple) - "Mitochondrial calcium uniporter controls AMPK activity and lipid metabolism"

3:25-3:50

Joe Baur, PhD (UPenn) - “Mitochondrial NAD metabolism”

3:50-4:15

Haiming Cao, PhD (NHLBI/NIH) - "Regulation of metabolic homeostasis by long non-coding RNAs"

 

 

4:15-4:30pm

COFFEE BREAK

 

 

4:30-6:15pm

SYMPOSIUM 3: IMMUNOLOGY & INFECTION
Session Chair: Robert O'Doherty, PhD (UPitt)

4:30-4:55

Greg Delgoffe, PhD (UPitt) - "Mitochondria as key immunometabolic contributors to the avoidance of T cell exhaustion in cancer"

4:55-5:20

Anuradha Ray, PhD (UPitt) - "Mitochondrial control of airway immune tolerance"

5:20-5:45

Madhusudhan Sukumar, PhD (NIH/NCI) - "Metabolic reprogramming of anti-tumor immunity"

5:45-6:15

Abstract Talk: Elizabeth Novak, PhD (UPitt) = "NAD depletion in the intestinal epithelial results in mitochondrial dysfunction and influences the pathogenesis of experimental colitis"

Abstract Talk: Peter McGuire, PhD (NHGRI) - "Cytochrome c oxidase activity is a metabolic checkpoint during cell activation with heterogeneous consequences in effector T-cells"

Abstract Talk: Tal Yardeni, PhD (Children's Hospital of Philadelphia) - "Communicating with your ancestors: mitochondrial influence on the microbiome"

 

 

6:15-8:00pm

POSTER SESSION

6:15-7:00

Odd numbered posters

7:00-7:45

Even numbered posters

 


Music by the Kassia Ensemble // Hors d'oeuvres and Drinks