Vascular Medicine Institute
University of Pittsburgh
BST E1240
200 Lothrop Street
Pittsburgh, PA 15261
Phone: 412-383-5853
Fax: 412-648-5980

Prem Soman, MD




Prem Soman, MD

Associate Professor of Medicine,
Division of Cardiology

Associate Professor of Clinical and Translational Science

Director, Nuclear Cardiology

Director, Advanced Cardiac Imaging Fellowship

A-429 Scaife Hall
200 Lothrop Street
Pittsburgh, PA 15213

Phone: 412-647-3435
Fax: 412-647-0481
Email: somanp@upmc.edu

UPMC Profile



After initial medical training at the JN Medical College, Karnatak University, Belgaum, India, and the Postgraduate Institute of Medical Education and Research, Chandigarh, India, Dr. Soman trained as a clinical research fellow at the Northwick Park Hospital and Institute of Medical Research, Harrow, UK. He was awarded a PhD from the University of Surrey, Guildford, UK. He moved to the US in 2000, and completed Internal Medicine residency at the Lehigh Valley Hospital, Allentown, PA and fellowships in Cardiology and Advanced Cardiac Imaging at Tufts Medical Center, Boston, MA. He was recruited to UPMC in 2005.

Clinical Interests

Dr. Soman practices clinical cardiology, nuclear cardiology and echocardiography at the UPMC Presbyterian Hospital, with areas of focus in the noninvasive diagnosis and risk stratification of coronary artery disease, heart failure and valvular disease, and the management of cardiac disease in patients with chronic kidney disease. Under his direction, the nuclear cardiology laboratory performs high-volume, state-of-the art imaging, and is a national leader in clinical research including the use of a new generation, solid-state SPECT camera and innovative imaging protocols that have enabled significant reductions in radiation dose to patients.
He was selected “Best Doctors of Pittsburgh” in 2013 and 2014.

Academic and Research Interests

Dr. Soman is widely recognized for his contributions to the field of nuclear cardiology. He has co-authored several original research papers, invited editorials, book chapters, national guidelines (American Society of Nuclear Cardiology) and appropriate use criteria (American College of Cardiology). His leadership roles include:

Dr. Soman’s research focuses on the use of radionuclide-based imaging techniques in cardiac diseases, particularly heart failure. Current interests includes the use of myocardial SPECT imaging for left ventricular dyssynchrony assessment, an area in which his group has contributed seminal work (Mati Friehling, Young Investigator Award, ASNC 2010; Saurabh Malhotra, Young Investigator Award, ASNC 2013).

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The figure shows left ventricular dyssynchrony assessment using phase analysis of myocardial SPECT in a patient with right ventricular pacing. The upper panel shows a wide phase histogram. The bottom panel shows the sequence of left ventricular mechanical activation overlaid on a perfusion polar map. As expected in a patient with right ventricular pacing, activation begins at the left ventricular apex. All quantitative parameters are automatically derived from a standard myocardial perfusion study.


Soman P. Can the past inform the future of nuclear cardiology? A critical look at the state of our field. Editor’s page, Journal of Nuclear Cardiology 2014;21: 667

Soman P. Adapting to a changing healthcare environment. Imaging Council Chairman’s page. Journal of the American College of Cardiology 2014;7: 854

Malhotra S, Sharma R, Kliner D, Follansbee WP, Soman P. Relationship between silent myocardial ischemia and coronary artery disease risk factors. Journal of Nuclear Cardiology 2013; 5: 731

Ludwig DR, Friehling M, Schwartzman D, Saba S, Follansbee WP, Soman P. On the importance of gating for the assay of left ventricular dyssynchrony using SPECT. Journal of Nuclear Medicine 2012; 53: 1892

Friehling M, Chen J, Saba S, Bazaz R, Schwartzman D, Adelstein E, Garcia EV, Follansbee WP, Soman P. A prospective pilot study to evaluate the relationship between acute change in LV synchrony after cardiac resynchronization therapy and patients outcome using a single-injection gated-SPECT protocol. Circulation CV imaging 2011; 4: 532

Chen J, Garcia EV, Bax JJ, Iskandrian AE, Borges-Neto S, Soman P. Major Achievements in nuclear cardiology: SPECT myocardial perfusion imaging for the assessment of left ventricular mechanical dyssynchrony. Journal of Nuclear Cardiology 2011; 18:685

Holly TA, Abbott BA, Al-Mallah M, Brown KA, Calnon DA, Cohen MC, DiFilippo FP, Ficaro EP, Freeman ME, Hendel RC, Jain D, Leonard SM, Nichols KJ, Polk DM, Soman P.  ASNC Imaging Guidelines for Nuclear Cardiology: SPECT. Journal of Nuclear Cardiology 2010; 17:941

Soman P, Lahiri A, Mieres JH, Calnon DA, Wolinksy D, Beller GA, Sias T, Burnham K, Conway L, McCullough P, Daher E, Walshh MN, Wight J, Heller G, Udelson JE. Etiology and pathophysiology of new-onset heart failure: Evaluation by myocardial perfusion imaging. Journal of Nuclear Cardiology 2009; 16:82

Soman P, Taillefer R, DePuey EG, Udelson JE, Lahiri A. Enhanced detection of reversible perfusion defects by Tc-99m sestamibi compared to Tc-99m tetrofosmin during vasodilator stress SPECT imaging in mild to moderate coronary artery disease. Journal of the American College of Cardiology 2001;  37: 458.