Scott Laboratory
Contact
Lab phone: 412-648-8018
Lab address: E1200 Biomedical Science Tower (Starzl BST), 200 Lothrop Street, Pittsburgh, PA 15261
Available Position(s): POSTDOCTORAL ASSOCIATE
Research
Dr. Scott’s work focuses on the intrinsic mechanisms that regulate mitochondrial protein acetylation, and how this fundamental alteration affects organelle function at the cellular and tissue level. In particular, he is interested in the coordination between acetylation levels and mitophagy, a quality control mechanism that mediates the removal of dysfunctional mitochondrial organelles. Dr. Scott’s lab has recently discovered that GCN5L1, a mitochondrial protein that promotes lysine acetylation, regulates the transcriptional machinery of mitophagy.
See also: Center for Metabolism and Mitochondrial Medicine
People
PRINCIPAL INVESTIGATOR |
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Assistant Professor of Medicine, Division of Cardiology scotti2@upmc.edu | 412-648-7691 |
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FACULTY |
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JANET MANNING, PhD Research Assistant Professor manningj@pitt.edu | 412-648-8018 |
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POSTDOCS / FELLOWS |
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DHARENDRA THAPA, PhD Postdoctoral Associate thapad@pitt.edu | 412-648-8018 |
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BINGXIAN XIE, PhD Postdoctoral Associate bix8@pitt.edu | 412-648-8018 |
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RESEARCH STAFF |
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MIKE STONER Lab Manager / Research V mws13@pitt.edu | 412-648-8018 |
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